Vitamin E increases the absorption, intake and storage of vitamin A, and may protect against the vitamin A redundancy disease, however, these effects have been still discussed upon.
The use of vitamin E dosages greater than 10IU/kg of body weight may slow response to the treatment therapy with iron in children suffering from iron-deficiency anemia and may result in hemolytic anemia due to vitamin E deficiency in children treated with iron supplements. Vitamin E and its metabolites may protect against the action of vitamin K. Patients who take oral anticoagulants have risk of hemorrhage after taking the large dose of vitamin E. In healthy volunteers, vitamin E did not change clotted blood process.
The excessive use of mineral oil may decrease the vitamin E absorption.